van Mil Group

Curriculum Vitae

Since 2011, Saskia W.C. van Mil is working as an Associate Professor at the Department of Metabolic Diseases, University Medical Center Utrecht, The Netherlands. Her research focus is on the role of the nuclear receptor and bile acid sensor FXR in gastro-intestinal disease.

2007-2011, Assistant Professor, Department of Metabolic Diseases, UMC Utrecht. NWO-VENI: Reproductive hormones and FXR: the yin and yang of bile homeostasis?

2004-2007, Post-doctoral fellow Imperial College London, United Kingdom in the groups of Prof. Malcolm Parker and Prof Catherine Williamson. She studied the role of the nuclear receptor and bile salt sensor FXR in intrahepatic cholestasis of pregnancy.

1999-2004, PhD student, title: ‘Novel insights in familial cholestasis syndromes.’ During her PhD-project, she investigated the genetic basis of childhood cholestasis syndromes, diseases in which bile salt homeostasis is impaired. Amongst others, she identified ABCB11 (BSEP; bile salt export pump) as a gene involved in Benign Recurrent Intrahepatic Cholestasis type 2 (BRIC2). Supervisors: Dr. L.W.J. Klomp, Dr. R.H.J. Houwen and Prof. R.Berger.

1993-1999, University degree Medical Biology, Utrecht University.

 

Grants:

2012-2014: Wilhelmina Children’s Hospital Research Fund. Title: Selective FXR ligands, drug-discovery for inflammatory bowel disease.

2012-2014: Host of Marie Curie Intra-European Fellow (FP7) Alexandra Milona.

2011-2016: VIDI/Aspasia, Netherlands’ Organisation for Scientific Research. Title: Towards FXR-mediated therapeutic intervention: Understanding how FXR integrates metabolic, endocrine and inflammatory signalling.

2011-2016: Utrecht University Support Grant.

2007-2010: VENI, Netherlands’ Organisation for Scientific Research. Title: Reproductive hormones and FXR: the yin and yang of bile homeostasis?

2007-2009: UMC Utrecht internalisation grant. Travel grant for members of Dr. van Mil/Dr.Klomp and Prof. Williamson’s group, greatly facilitating the exchange of expertise.

2005-2007:      Marie Curie Intra-European Fellowship (FP7): 2-year funding for post-doc project. Title: The role of reproductive hormones and gestation in bile homeostasis.