Burgering Group

Selected papers Burgering Group

 

Kruiswijk F, Hasenfuss SC, Sivapatham R, Baar MP, Putavet D, Naipal KA, van den Broek NJ, Kruit W, van der Spek PJ, van Gent DC, Brenkman AB, Campisi J, Burgering BM, Hoeijmakers JH, de Keizer PL Oncogene. Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling. 2015 Aug 17. doi: 10.1038/onc.2015.282. [Epub ahead of print]

Kloet DE, Polderman PE, Eijkelenboom A, Smits LM, van Triest MH, van den Berg MC, Groot Koerkamp MJ, van Leenen D, Lijnzaad P, Holstege FC, Burgering BM. Biochem J. FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1). 2015 Jul 15;469(2):289-98. doi: 10.1042/BJ20140831. Epub 2015 May 20.

Charitou P, Rodriguez-Colman M, Gerrits J, van Triest M, Groot Koerkamp M, Hornsveld M, Holstege F, Verhoeven-Duif NM, Burgering BM. EMBO Rep. FOXOs support the metabolic requirements of normal and tumor cells by promoting IDH1 expression. 2015 Apr;16(4):456-66. doi: 10.15252/embr.201439096. Epub 2015 Feb 3.

Putker M, Vos HR, van Dorenmalen K, de Ruiter H, Duran AG, Snel B, Burgering BM, Vermeulen M, Dansen TB. Antioxid Redox Signal. Evolutionary Acquisition of Cysteines Determines FOXO Paralog-Specific Redox Signaling. 2015 Jan 1;22(1):15-28. doi: 10.1089/ars.2014.6056. (link to paper)

Coomans de Brachène A, Bollaert E, Eijkelenboom A, de Rocca Serra A, van der Vos KE, Burgering BM, Coffer PJ, Essaghir A, Demoulin JB. Biochem J. The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway. 2014 May 15;460(1):25-34. doi: 10.1042/BJ20131467. (link to paper)

van den Berg MC, Burgering BM. Cell Adh Migr. CCM1 and the second life of proteins in adhesion complexes. 2014 Mar 31;8(2). [Epub ahead of print] Review.
 (link to paper)

Eijkelenboom A, Mokry M, Smits LM, Nieuwenhuis EE, Burgering BM. Cell Rep. FOXO3 selectively amplifies enhancer activity to establish target gene regulation. 2013 Dec 26;5(6):1664-78. doi: 10.1016/j.celrep.2013.11.031. Epub 2013 Dec 19. (link to paper)

van Boxtel R, Gomez-Puerto C, Mokry M, Eijkelenboom A, van der Vos KE, Nieuwenhuis EE, Burgering BM, Lam EW, Coffer PJ.Cell Death Differ. FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis.2013 Sep;20(9):1219-29. doi: 10.1038/cdd.2013.81. Epub 2013 Jul 5. (link to paper)

Zwartkruis FJ, Burgering BM. Cell Res.Ras and macropinocytosis: trick and treat.2013 Aug;23(8):982-3. doi: 10.1038/cr.2013.79. Epub 2013 Jun 18. (link to paper)

van den Berg MC, van Gogh IJ, Smits AM, van Triest M, Dansen TB, Visscher M, Polderman PE, Vliem MJ, Rehmann H, Burgering BM.J  Biol Chem. The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex. 2013 Jul 26;288(30):21729-41. doi: 10.1074/jbc.M113.463885. Epub 2013 Jun 14. (link to paper)

Eijkelenboom A, Mokry M, de Wit E, Smits LM, Polderman PE, van Triest MH, van Boxtel R, Schulze A, de Laat W, Cuppen E, Burgering BM. Mol Syst Biol. Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling. 2013 Jan 22;9:638. doi: 10.1038/msb.2012.74. (link to paper)

Putker M, Madl T, Vos HR, de Ruiter H, Visscher M, van den Berg MC, Kaplan M, Korswagen HC, Boelens R, Vermeulen M, Burgering BM, Dansen TB. Mol Cell. Redox-dependent control of FOXO/DAF-16 by transportin-1. 2013 Feb 21;49(4):730-42. doi: 10.1016/j.molcel.2012.12.014. Epub 2013 Jan 17. (link to paper)

Eijkelenboom A, Burgering BM.Nat Rev Mol Cell Biol. FOXOs: signalling integrators for homeostasis maintenance. 2013 Feb;14(2):83-97. doi: 10.1038/nrm3507. Epub 2013 Jan 17. Review. (link to paper)

van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen LP, Groot Koerkamp MJ, Braat AK, Dansen TB, Holstege FC, Gebhardt R, Burgering BM, Coffer PJ. Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy. Nat Cell Biol. 2012 Aug;14(8):829-37. doi: 10.1038/ncb2536. Epub 2012 Jul 22. (link to paper)

Huang HY, Houwing S, Kaaij LJ, Meppelink A, Redl S, Gauci S, Vos H, Draper BW, Moens CB, Burgering BM, Ladurner P, Krijgsveld J, Berezikov E, Ketting RF. Tdrd1 acts as a molecular scaffold for Piwi proteins and piRNA targets in zebrafish. EMBO J. 2011 Jul 8;30(16):3298-308. doi: 10.1038/emboj.2011.228. (link to paper)

Kloet DE, Burgering BM.The PKB/FOXO switch in aging and cancer. Biochim Biophys Acta. 2011 Nov;1813(11):1926-37. Epub 2011 Apr 27. Review. (link to paper)

Kress TR, Cannell IG, Brenkman AB, Samans B, Gaestel M, Roepman P, Burgering BM, Bushell M, Rosenwald A, Eilers M. The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis.Mol Cell. 2011 Feb 18;41(4):445-57. (link to paper)

Szypowska AA, de Ruiter H, Meijer LA, Smits LM, Burgering BM. Oxidative stress-dependent regulation of Forkhead box O4 activity by nemo-like kinase. Antioxid Redox Signal. 2011 Feb 15;14(4):563-78. (link to paper)

de Keizer PL, Burgering BM, Dansen TB. Forkhead box o as a sensor, mediator, and regulator of redox signaling. Antioxid Redox Signal. 2011 Mar 15;14(6):1093-106. (link to paper)

van den Berg MC, Burgering BM Integrating opposing signals toward Forkhead box O. Antioxid Redox Signal. 2011 Feb 15;14(4):607-21 (link to paper)

de Keizer PL, Packer LM, Szypowska AA, Riedl-Polderman PE, van den Broek NJ, de Bruin A, Dansen TB, Marais R, Brenkman AB, Burgering BM.
Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence. Cancer Res. 2010 Nov 1;70(21):8526-36. (link to paper)

Brenkman AB, van den Broek NJ, de Keizer PL, van Gent DC, Burgering BM. The DNA damage repair protein Ku70 interacts with FOXO4 to coordinate a conserved cellular stress response. FASEB J. 2010 Nov;24(11):4271-80. (link to paper)

Dansen TB, Smits LM, van Triest MH, de Keizer PL, van Leenen D, Koerkamp MG, Szypowska A, Meppelink A, Brenkman AB, Yodoi J, Holstege FC, Burgering BM. Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity. Nat Chem Biol. 2009 Sep;5(9):664-72. (link to paper)

Hoogeboom D, Burgering BM
Should I stay or should I go: beta-catenin decides under stress. Biochim Biophys Acta. 2009 Dec 1796(2):63-74 (link to paper)

van Gorp AG, van der Vos KE, Brenkman AB, van den Broek N, Zwartkruis F, Hershey JW, Burgering BM, Calkhoven CF, Coffer PJ AGC kinases regulate phosphorylation and activation of eukaryotic translation initiation factor 4B.Oncogene. 2009, Jan 8;28(1):95-106 (link to paper)

Brenkman AB, de Keizer PL, van den Broek NJ, van der Groep P, van Diest PJ, van der Horst A, Smits AM, Burgering BM The peptidyl-isomerase Pin1 regulates p27kip1 expression though inhibition of Forkhead box O tumor suppressors.Cancer Res. 2008, Sep 15;68(18):7597-605 (link to paper)

Dansen TB, Burgering BM
Unravelling the tumor-suppressive functions of FOXO proteins.Trends Cell Biol. 2008, Sep:18(9):421-9 (link to paper)

Brenkman AB, de Keizer PL, van den Broek NJ, Jochemsen AG, Burgering BM
Mdm2 induces mono-ubiquitination of FOXO4.PLoS ONE 2008, Jul 30;3(7):e2819 (link to paper)

Boudewijn M.T.Burgering
A brief introduction to FOXOlogy.Oncogene 2008, 27, 2258-2262 (link to paper)

Hoogeboom D, Essers MA, Polderman PE, Voets E, Smits LM, Burgering BM
Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity. J Biol Chem. 2008 Apr 4;283(14):9224-30 (link to paper)

Rene H. Medema and Boudewijn M.T.Burgering
The X Factor: Skewing X Inactivation towards Cancer. Cell. 2007 June, 29;129(7):1253-4 (link to paper)

Arjan B. Brenkman and Boudewijn M.T.Burgering
Live Longer through PHAsting.Cell Metabolism. 2007 June; 5(6):407-9 (link to paper)

Armando van der Horst and Boudewijn M.T.Burgering
Stressing the role of FoxO proteins in lifespan and disease. Nature Reviews. 2007 June;8(6):440-50 (link to paper)

Oona Delpuech, Beatrice Griffiths, Philip East, Abdelkader Essafi, Eric W.-F.Lam, Boudewijn Burgering, Julian Downward and Almut Schulze
Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression.. Mol Cell Biol. 2007 Jul;27(13):4917-30 (link to paper)

Armando van der Horst, Jolanda M. Schavemaker, Wendy Pellis-van Berkel and Boudewijn M.T.Burgering
The Caenorhabditis elegans nicotinamidase PNC-1 enhances survival. .Mech Ageing Dev. 2007 Apr;128(4):346-9 (link to paper)

Paul J. Coffer and Boudewijn M.T.Burgering
Stressed marrow: FoxOs stem tumor growth. Nature Cell Biology.2007 Mar; 9(3):251-3 (link to paper)

Armando van der Horst, Alida M.M.de Vries-Smits, Arjan B.Brenkman, Miranda H.vanTriest, Niels van den Broek, Frederic Colland, Madelon M. Maurice and Boudewijn M.T.Burgering
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nature Cell Biology. 2006 Oct;8(10):1064-73 (link to paper)

Andrew Sunters, Patricia A. Madureira, Karen M. Pomeranz, Muriel Aubert, Jan J.Brosens, Simon J. Cook, Boudewijn M.T. Burgering, R. Charles Coombes and Eric W.-F. Lam
Paclitaxel-Induced Nuclear Translocation of FOXO3a in Breast Cancr Cell Is Mediated by c-Jun NH2-Terminal Kinase and Akt. Cancer Research. 2006 Jan 66;212-220 (link to paper)

Bucko-Justyna M, Lipinski L, Burgering BM, Trzeciak L
Characterization of testis-specific serine-threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling. FEBS J. 2005 Dec;272(24):6310-23 (link to paper)

Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, Korswagen HC
AFunctional interaction between beta-catenin and FOXO in oxidative stress signaling. Science. 2005 May 20;308(5725):1181-4 (link to paper)

Kuiperij HB, van der Horst A, Raaijmakers J, Weijzen S, Medema RH, Bos JL, Burgering BM, Zwartkruis F
Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP. Oncogene. 2005 Mar 17;24(12):2087-95 (link to paper)

van den Heuvel AP, Schulze A, Burgering BM
Direct control of caveolin-1 expression by FOXO transcription factors. Biochem J. 2005 Feb 1;385(Pt 3):795-802. (link to paper)

Essers MA, Weijzen S, de Vries-Smits AM, Saarloos I, de Ruiter ND, Bos JL, Burgering BM.
FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. EMBO J. 2004 Nov 11 (link to paper)

Bos JL, Burgering BM.
Molecular mechanisms in signal transduction and cancer. EMBO Rep. 2004 Sep;5(9):855-9 (link to paper)

T.B. Dansen, G.J. P. L. Kops, S. Denis, N. Jelluma, R.J.A. Wanders, J.L. Bos, B.M.T. Burgering and K.W. A. Wirtz. Regulation of sterol carrier protein gene expression by the Forkhead transcription factor FOXO3a. Journal of Lipid Research (2004) 45: 81-88 (link to paper)

A. van der Horst, L.G.J. Tertoolen, L.M.M. de Vries-Smits, R.A. Frye, R.H. Medema and B.M.T. Burgering.
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1. J Biol Chem. 2004 May 4 (link to paper)

Brenkman AB, Burgering BM.FoxO3a eggs on fertility and aging.
Trends Mol Med. 2003 Nov;9(11):464-7. (link to paper)

M. Schmidt, S.F. de Mattos, A. van der Horst, R. Klompmaker, G.J. Kops, E.W. Lam, B.M. Burgering, R.H. Medema. Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.
Mol Cell Biol (2002) 22(22): 7842-52. (link to paper)

A.P. van den Heuvel, A.M. de Vries-Smits, P.C. van Weeren, P.F. Dijkers, K.M. de Bruyn, J.A. Riedl, B.M. Burgering. Binding of protein kinase B to the plakin family member periplakin.
J Cell Sci. (2002) 115(Pt 20): 3957-3966. (link to paper)

G.J.P.L. Kops, T.B. Dansen, P.E. Polderman, I. Saarloos, K.W.A. Wirtz, P.J. Coffer, T.-T. Huang, J.L. Bos, R.H. Medema, B.M.T. Burgering. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress.
Nature (2002) 419(6904): 316-321. (link to paper)

F.J. Staal, R.B. van der Luijt, M.R. Baert, J. van Drunen, H. van Bakel, E. Peters, I. de Valk, H.K. van Amstel, M.J. Taphoorn, G.H. Jansen, C.W. van Veelen, B. Burgering, G.E. Staal. A novel germline mutation of PTEN associated with brain tumours of multiple lineages.
Br. J. Cancer (2002) 86(10): 1586-91. (link to paper)

B.M.T. Burgering, G.J. Kops. Cell Cycle and Death Control: Long Live Forkhead. Review.
TIBS (2002) 27(7): 352-60. (link to paper)

M. Stahl, P.F. Dijkers, G.J. Kops, S.M. Lens, P.J. Coffer, B.M. Burgering, R.H. Medema. The Forkhead Transcription Factor FoxO Regulates Transcription of p27(Kip1) and Bim in Response to IL-2.
J. Immunol. (2002) 168(10): 5024-31. (link to paper)

G.J. Kops, R.H. Medema, J. Glassford, M.A. Essers, P.F. Dijkers, P.J. Coffer, E.W Lam, B.M.T. Burgering. Control of Cell Cycle Exit and Entry by Protein Kinase B-Regulated Forkhead Transcription Factors.
Mol Cell Biol (2002) 22(7): 2025-36. (link to paper)

N.D. de Ruiter, B.M.T. Burgering, J.L. Bos. Regulation of the Forkhead Transcription Factor AFX by Ral-Dependent Phosphorylation of Threonines 447 and 451.
Mol Cell Biol (2001) 21(23): 8225-35. (link to paper)

B. Alvarez, C. Martinez-A, B.M.T. Burgering, A.C. Carrera. Forkhead transcription factors contribute to execution of the mitotic programme in mammals.
Nature (2001) 413(6857): 744-7. (link to paper)

A.M. Brownawell, G.J. Kops, I.G. Macara, B.M. Burgering. Inhibition of nuclear import by protein kinase b (akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.
Mol Cell Biol (2001) 21(10): 3534-46. (link to paper)

A. Akhmanova, C.C. Hoogenraad, K. Drabek, T. Stepanova, B. Dortland, T. Verkerk, W. Vermeulen, B.M. Burgering, C.I. de Zeeuw, F. Grosveld, N. Galjart. Clasps are clip-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.
Cell (2001) 104(6): 923-35. (link to paper)


G.J. Kops, B.M. Burgering. Forkhead transcription factors are targets of signalling by the proto-oncogene PKB (C-AKT).
J. Anat. (2000) 197 Pt 4:571-4. Review. (link to paper)

P.F. Dijkers, R.H. Medema, C. Pals, L. Banerji, N.S. Thomas, E.W. Lam, B.M. Burgering, J.A. Raaijmakers, J.W. Lammers, L. Koenderman, P.J. Coffer. Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).
Mol. Cell Biol. (2000) (24):9138-48. (link to paper)

N.D. de Ruiter, R.M. Wolthuis, H. van Dam, B.M. Burgering, J.L. Bos. Ras-dependent regulation of c-Jun phosphorylation is mediated by the Ral guanine nucleotide exchange factor-Ral pathway.
Mol. Cell Biol. (2000) (22):8480-8. (link to paper)

E. M. Genot, C. Arrieumerlou, G. Ku, B. M. T. Burgering, A. Weiss, IJ. M. Kramer. The T-cell receptor regulates akt (protein kinase B) via a pathway involving rac1 and phosphatidylinositide 3-kinase.
Mol Cell Biol. 20(2000), 5469-5478. (link to paper)

M. Collado, R.H. Medema, I. Garcia-Cao, M.L.N. Dubuisson, M. Barradas, J. Glassford, C. Rivas, B.M.T. Burgering, M. Serrano, E.W.-F. Lam. Inhibition of the phosphoinositide 3-kinase pathay induces a senescence-like arrest mediated by p27Kip1.
J.Biol.Chem. 275(2000), 21960-21968. (link to paper)

R.H. Medema, G.J.P.L. Kops, J.L. Bos, B.M.Th. Burgering. The forkhead transcription factor AFX regulates p27kip1 to mediate cell cycle regulation by Ras and PKB.
Nature 404 (2000) 782-787. (link to paper)